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Program management before the plan breaks

We integrate CMC, nonclinical, regulatory, and clinical workstreams so founders stay on the science and investors see a program they can underwrite.

Portfolio, Program & Alliance Management

Program management in biotech is not status meetings. It is the discipline that sequences CMC, nonclinical, regulatory, and clinical work, names the critical path, and surfaces risk while there is still time to act. Teams that wait until 'we are bigger' usually discover the gap in diligence or at IND.

BioVertex embeds as Head of Program Management or as an operating partner: integrated Gantt charts, stage-gate reviews, KPI packs for executives and boards, and alliance management when CROs, CDMOs, or academic partners are on the critical path.

We have run this function inside large pharma and CRISPR-era biotech. The frameworks are fit-for-purpose: enough structure to keep a Seed company honest, not an enterprise PMO that burns runway.

What you get

Who this is for

Pre-Seed to Series B companies layering external vendors, programs heading toward IND or a first-in-human study, and VC-backed teams that need operational muscle without a full-time senior hire yet.

Related reading: Why Early-Stage Startups Need Program Management Sooner Than They Think. VC diligence and portfolio buildout live on For VC Firms.

Questions we hear

When you start stacking CMC, nonclinical, regulatory, and external CRO/CDMO work — typically late Pre-Seed through Seed. Waiting until Series B usually means untracked dependencies and a diligence story you cannot defend.
Strategic. We connect company vision to operational reality: roadmaps, risk, cross-functional decisions (DACI/RACI), and portfolio-level resource calls. Coordination without judgment is not enough at this stage.
Yes. Portfolio-level views are a core offer: what is on the critical path across assets, where capital is actually going, and which gates are real.
We complement internal coordinators. We install the operating system (timeline, gates, board pack) and coach the team so the function survives after we step back.

Scope this with us

Free 30-minute consult. Honest read on whether BioVertex is the right operator for this work.

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